Collateral Missing Value Estimation (CMVE) Software

M. S. B. Sehgal, I. Gondal, and L. Dooley, "Collateral Missing Value Imputation: a new robust missing value estimation algorithm for microarray data," Bioinformatics, vol. 21(10), pp. 2417-2423, 2005.


The CMVE toolbox estimates missing values by using correlation structure of the data.. Even though the software was tested for microarray data. It can be used to impute missing values in any correlated data. Further details about CMVE can be found in our Bioinformatics paper.


  1. Imputes missing values in the correlated data.

  2. It improves the accuracy of Gene Regulatory Network Modelling, Class Prediction, Gene Selection, Clustering and other subsequent analysis methods.

For Windows: Click here to download CMVE v1.4 [released on 13/10/2006]

Click here to download CMVE v1.1 [released on 22/08/2006]

Click here to download Unix/Linux compatible CMVE version.

There is a CMVE Google discussion group at

which can be used as a platform to discuss issues regarding CMVE.

Please feel free to email me to notify bugs, improvements or to discuss any problem regarding the software.

Email: or